Rationale (course perspectives):



Hematology is the branch of medicine concerned with the study of blood and blood forming organs and blood diseases ranging from anemia's to blood cancers.

In this module the student will be exposed to basic knowledge of the structure and function of the blood cells, the normal physiology and biochemistry   of blood and blood components, and also the Hematopathology of different diseases related to blood.

 


Specific objectives:

By the end of this module students are expected to:

 

  •  Describe the normal histology of bone marrow and the sites of haempoiesis in relation to age groups.
  • Overview the general structure and histology of the Reticulo-endothelial system and its locations and different components.
  • Describe the processes of normal haempoiesis and their requirements and to discuss the role of hemoglobin in the transport of oxygen in the red blood cells.
  • Describe the structure, metabolism and function of haemoglobin .
  • Describe folate and Vit B12 metabolism and function.
  •  Describe the features and functions of the different types of cells in the blood and identify their normal morphology in the lab.
  • Give an account of classification, causes, pathogenesis and diagnosis of different types of anemias.
  • Discuss benign WBCS disorders and their causes.
  •  Discuss blood malignancies in terms of acute and chronic leukaemia.
  • Mention the presentation (symptoms and signs) and diagnosis of Hodgkin’s and Non-Hodgkin’s lymphomas.
  • Define  and overview the presentation and diagnosis of Myeloproliferative disorders and Multiple Myeloma
  •  Define and discuss the process of normal hemostasis (blood coagulation) .
  • Explain the causes of excessive bleeding, bleeding tendencies and thrombosis.
  • Discuss platelets and coagulation disorders.
  • Demonstrate and measure basic coagulation test in the lab in terms of: PT, PTT and bleeding time.
  • Mention the types of plasma proteins and related disturbances.
  • List the blood groups types and overview the molecular and hereditary basis of the ABO and Rhesus blood groups and demonstrate how to identify each in the lab.
  •  Discuss the role of blood banks, the selection of blood donors and review different blood products.
  • Discuss the causes and complications of transfusion reactions.
  • Discuss the pathology of hemolytic disease of the newborn.
  • Overview the endemic blood born infections ( Malaria and leshmania).
  • Review the basic immunology and discuss some immunological disorders(Immune deficiency, Autoimmune disease, transplant rejection and Diagnostic immunology